Thorne Research Indole-3-Carbinol 60 Veggie Caps

• Dietary Supplement
• Hypoallergenic
• To Support Estrogen Metabolism
• Maintains Optimal 2-Hydroxy/16-Hydroxy Estrogen Ratios
• Found in Cabbage Family Vegetables, it's a Source of DIM
• Nutritional Support for Liver Detoxification
• Made Without Flowing Agents that can Inhibit Bioavailability

Indole-3-carbinol (I3C) is a compound found in high concentrations in vegetables of the Brassica family, including broccoli, cauliflower, Brussels sprouts, and cabbage.

As a dietary supplement, I3C provides key nutritional support   for liver detoxification. It also plays an important role in supporting female   reproductive health. The majority of ingested I3C is absorbed in the small   intestine as diindolylmethane (DIM), which is thought to be the primary   contributor to I3C's beneficial properties. DIM has been shown to selectively bind to estrogen receptors and may act as an estrogen antagonist at   physiological concentration.

In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy   estrogen. The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found   postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio   were most likely to maintain good female health.

Preliminary studies   have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week phase I trial conducted on 17 women found a 66-percent increase in   urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.

Take 1 capsule one to two times daily or as recommended by your health-care practitioner.

Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.